Preheat your oven to 400°F (200°C). Pat the chicken breasts dry with paper towels.
Set up your breading station with flour seasoned with salt, pepper, garlic powder, onion powder, and paprika; whisked eggs; and panko breadcrumbs.
Dip each piece of chicken into the flour mixture, then into the egg wash, and finally roll it in panko.
Arrange the breaded chicken on a baking sheet and bake for about 25 minutes until golden brown.
Combine honey, hot sauce, and apple cider vinegar in a saucepan over low heat until warmed through.
Drizzle the hot honey sauce over the baked chicken before serving.